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1

Methotrexate bound to carbon particles used for treating cancers with lymph node metastases in animal experiments and a clinical pilot study

Akeo Hagiwara, Toshio Takahashi, Kiyoshi Sawai, Chouhei Sakakura, Masakazu Hoshima, Takayuki Ohyama, Masaharu Ohgaki, Tsutomu Imanishi, Akira Yamamoto, Shozo Muranishi

Journal:

Year:

1996

Language:

english

File:

PDF, 906 KB

english, 1996

2

Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines

Elizabeth A. Sweeney, Chouhei Sakakura, Tsutomu Shirahama, Atsushi Masamune, Hideki Ohta, Sen-itiroh Hakomori, Yasuyuki Igarashi

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

3

Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis

Chouhei Sakakura, Elizabeth A. Sweeney, Tsutomu Shirahama, Yasuyuki Igarashi, Sen-itiroh Hakomori, Hirohisa Nakatani, Hiroyuki Tsujimoto, Tsutomu Imanishi, Masaharu Ohgaki, Takakuki Ohyama, Junya Yama

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 553 KB

english, 1996

4

Plasma levels of activated protein C–protein C inhibitor complex in patients with hypercoagulable states

Rika Watanabe, Hideo Wada, Miho Sakakura, Yoshitaka Mori, Takahiro Nakasaki, Yoshinaga Okugawa, Esteban C. Gabazza, Tatsuya Hayashi, Junji Nishioka, Koji Suzuki, Hiroshi Shiku, Tsutomu Nobori

Journal:

American Journal of Hematology

Year:

2000

Language:

english

File:

PDF, 108 KB

english, 2000

5

Increased plasma levels of tissue factor pathway inhibitor-activated factor X complex in patients with disseminated intravascular coagulation

Yoshinaga Okugawa, Hideo Wada, Tomohiro Noda, Miho Sakakura, Takahiro Nakasaki, Rika Watanabe, Hiroshi Deguchi, Esteban C. Gabazza, Yoshitaka Mori, Masakatsu Nishikawa, Katsumi Deguchi, Tsutomu Nobori

Journal:

American Journal of Hematology

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

6

Relation between cyclooxygenase-2 expression and tumor invasiveness and patient survival in transitional cell carcinoma of the urinary bladder

Tsutomu Shirahama, Jun-ichirou Arima, Suminori Akiba, Chohei Sakakura

Journal:

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

7

Comparative histochemical study of alimentary tracts with special reference to the mucous neck cells of the stomach

Tatsuo Suganuma, Tsutomu Katsuyama, Masanori Tsukahara, Masae Tatematsu, Yasunori Sakakura, Professor Fusayoshi Murata

Journal:

Developmental Dynamics

Year:

1981

Language:

english

File:

PDF, 1.45 MB

english, 1981

8

Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer

Chouhei Sakakura, Akeo Hagiwara, Koji Miyagawa, Susumu Nakashima, Tetsuji Yoshikawa, Shuichi Kin, Yuenn Nakase, Kosei Ito, Hisakazu Yamagishi, Shujiro Yazumi, Tsutomu Chiba, Yoshiaki Ito

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 540 KB

english, 2005

9

Ultrastructural analysis of the membrane insertion of domain 3 of streptolysin O

Kachiko Sekiya, Takumi Akagi, Kiyoko Tatsuta, Eriko Sakakura, Tsutomu Hashikawa, Akio Abe, Hideaki Nagamune

Journal:

Microbes and Infection

Year:

2007

Language:

english

File:

PDF, 2.30 MB

english, 2007

10

Endoscopic local injection of a new drug delivery formulation, anticancer drug bound to carbon particles, for digestive cancers: Pilot study

Akeo Hagiwara, Toshio Takahashi, Kazuya Kitamura, Chouhei Sakakura, Morio Shirasu, Masaharu Ohgaki, Tsutomu Imanishi, Junya Yamasaki

Journal:

Journal of Gastroenterology

Year:

1997

Language:

english

File:

PDF, 3.71 MB

english, 1997

11

Restoration of RUNX3 enhances transforming growth factor-β-dependent p21 expression in a biliary tract cancer cell line

Kazunori Hasegawa, Shujiro Yazumi, Manabu Wada, Toshiharu Sakurai, Masaya Kida, Junichi Yamauchi, Hiroshi Hisatsune, Shinsuke Tada, Hiroshi Ida, Yuenn Nakase, Chohei Sakakura, Akeo Hagiwara, Tsutomu C

Journal:

Year:

2007

Language:

english

File:

PDF, 301 KB

english, 2007

12

Quantitative Analysis of Mucin and Lectin in Maxillary Sinus Fluids in Patients With Acute and Chronic Sinusitis

Jun Shinogi, Teruhiko Harada, Tsutomu Nonoyama, Chikako Kishioka, Yasuo Sakakura, Yuichi Majima

Journal:

The Laryngoscope

Year:

2001

Language:

english

File:

PDF, 94 KB

english, 2001

13

Overexpression ofbaxenhances the radiation sensitivity in human breast cancer cells

Chouhei Sakakura, Elizabeth A. Sweeney, Tsutomu Shirahama, Yasuyuki Igarashi, Sen-Ichiroh Hakomori, Hiroyuki Tsujimoto, Tsutomu Imanishi, Masaharu Ohgaki, Junya Yamazaki, Akeo Hagiwara, Kiyoshi Sawai,

Journal:

Year:

1997

Language:

english

File:

PDF, 485 KB

english, 1997

14

Overexpression ofBaxsensitizes breast cancer MCF-7 cells to cisplatin and etoposide

Chouhei Sakakura, Elizabeth A. Sweeney, Tsutomu Shirahama, Yasuyuki Igarashi, Sen-ichiroh Hakomori, Hiroyuki Tsujimoto, Tsutomu Imanishi, Masaharu Ogaki, Takayuki Ohyama, Junya Yamazaki, Akeo Hagiwara

Journal:

Year:

1997

Language:

english

File:

PDF, 491 KB

english, 1997

15

Infiltration of dendritic cells and NK cells into the sentinel lymph node in oral cavity cancer

Koichi Sakakura, Kazuaki Chikamatsu, Tsutomu Sakurai, Katsumasa Takahashi, Takaaki Murata, Noboru Oriuchi, Nobuhiko Furuya

Journal:

Year:

2005

Language:

english

File:

PDF, 455 KB

english, 2005

16

Expression of thymidylate synthase and dihydropyrimidine dehydrogenase in adenoid cystic carcinoma of the head and neck: Correlation with clinical outcome

Kazuaki Chikamatsu, Masato Shino, Koichi Sakakura, Kyoko Nakajima, Tsutomu Sakurai, Motoaki Miyashita, Nobuhiko Furuya

Journal:

Year:

2007

Language:

english

File:

PDF, 456 KB

english, 2007

17

The choleretic effects of N-acetylglucosaminides, major urinary metabolites of ursodeoxycholic acid, in bile fistula rats

Tomomichi Iwaki, Norio Hirabayashi, Norio Miyazawa, Yoshishige Takeuchi, Kaoru Ishizaki, Hiroo Sakakura, Hiroshi Kasai, Minoru Maeda, Tsutomu Araki

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 313 KB

english, 1998

18

Fabrication of three-dimensional 1 × 4 splitter waveguides inside a glass substrate with spatially phase modulated laser beam

Sakakura, Masaaki, Sawano, Tsutomu, Shimotsuma, Yasuhiko, Miura, Kiyotaka, Hirao, Kazuyuki

Journal:

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

19

Improved phase hologram design for generating symmetric light spots and its application for laser writing of waveguides

Sakakura, Masaaki, Sawano, Tsutomu, Shimotsuma, Yasuhiko, Miura, Kiyotaka, Hirao, Kazuyuki

Journal:

Year:

2011

Language:

english

File:

PDF, 601 KB

english, 2011

20

Selectivity of Sphingosine-Induced Apoptosis: Lack of Activity ofdl-erythyro-Dihydrosphingosine

Chouhei Sakakura, Elizabeth A. Sweeney, Tsutomu Shirahama, Akeo Hagiwara, Toshiharu Yamaguchi, Toshio Takahashi, Sen-itiroh Hakomori, Yasuyuki Igarashi

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 133 KB

english, 1998

21

Suppression of Bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation

Chouhei Sakakura, Elizabeth A. Sweeney, Tsutomu Shirahama, Sen-itiroh Hakomori, Yasuyuki lgarashi

Journal:

Year:

1996

Language:

english

File:

PDF, 537 KB

english, 1996

22

Reduced Cd4+Cd25+ T cells in patients with idiopathic thrombocytopenic purpura

Miho Sakakura, Hideo Wada, Isao Tawara, Tsutomu Nobori, Takashi Sugiyama, Norimasa Sagawa, Hiroshi Shiku

Journal:

Thrombosis Research

Year:

2007

Language:

english

File:

PDF, 200 KB

english, 2007

23

Subtotal gastrectomy for cancer located in the greater curvature of the middle stomach with prevention of the left gastric artery

Akeo Hagiwara, Tsutomu Imanishi, Chouhei Sakakura, Eigo Otsuji, Kazuya Kitamura, Hirosumi Itoi, Hisakazu Yamagishi

Journal:

The American Journal of Surgery

Year:

2002

Language:

english

File:

PDF, 151 KB

english, 2002

24

Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-XL gene expression

Tsutomu Shirahama, Chohei Sakakura, Elizabeth A. Sweeney, Masayuki Ozawa, Masakazu Takemoto, Kenryu Nishiyama, Yoshitada Ohi, Yasuyuki Igarashi

Journal:

Year:

1997

Language:

english

File:

PDF, 509 KB

english, 1997

25

Activity and Antigen Levels of Thrombin-Activatable Fibrinolysis Inhibitor in Plasma of Patients With Disseminated Intravascular Coagulation

Rika Watanabe, Hideo Wada, Yasuyuki Watanabe, Miho Sakakura, Takahiro Nakasaki, Yoshitaka Mori, Masakatsu Nishikawa, Esteban C. Gabazza, Tsutomu Nobori, Hiroshi Shiku

Journal:

Thrombosis Research

Year:

2001

Language:

english

File:

PDF, 105 KB

english, 2001

26

Immunohistochemical localization of cytokines and cell adhesion molecules in maxillary sinus mucosa in chronic sinusitis

Tsutomu Nonoyama, Teruhiko Harada, Jun Shinogi, Eiji Yoshimura, Yasuo Sakakura

Journal:

Auris Nasus Larynx

Year:

2000

Language:

english

File:

PDF, 472 KB

english, 2000

27

Synergistic hybrid catalyst for cyclic carbonate synthesis: Remarkable acceleration caused by immobilization of homogeneous catalyst on silica

Takahashi, Toshikazu, Watahiki, Tsutomu, Kitazume, Shoji, Yasuda, Hiroyuki, Sakakura, Toshiyasu

Journal:

Chemical Communications

Year:

2006

Language:

english

File:

PDF, 316 KB

english, 2006

28

Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines

Wada, Manabu, Yazumi, Shojiro, Takaishi, Shigeo, Hasegawa, Kazunori, Mitsutaka,, Ida, Hiroshi, Sakakura, Chohei, Ito, Kosei, Ito, Yoshiaki, Chiba, Tsutomu

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

29

Expression of thymidylate synthase and dihydropyrimidine dehydrogenase in oral squamous cell carcinoma: possible markers as predictors of clinical outcome

Sakakura, Koichi, Chikamatsu, Kazuaki, Shino, Masato, Sakurai, Tsutomu, Furuya, Nobuhiko

Journal:

Acta Oto-Laryngologica

Year:

2006

Language:

english

File:

PDF, 336 KB

english, 2006

30

Effect of Surrounded-Channel Structure on Electrical Characteristics of $c$ -Axis Aligned Crystalline In–Ga–Zn–O Field-Effect Transistor

Kobayashi, Yoshiyuki, Matsubayashi, Daisuke, Hondo, Suguru, Yamamoto, Tsutomu, Okazaki, Yutaka, Nagai, Masaharu, Sasagawa, Shinya, Ito, Daigo, Hata, Yuki, Hamada, Takashi, Arasawa, Ryo, Sakakura, Masa

Journal:

IEEE Electron Device Letters

Year:

2015

Language:

english

File:

PDF, 857 KB

english, 2015

31

Parallel Drawing of Multiple Bent Optical Waveguides Using a Spatial Light Modulator

Sakakura, Masaaki, Sawano, Tsutomu, Shimotsuma, Yasuhiko, Miura, Kiyotaka, Hirao, Kazuyuki

Journal:

Japanese Journal of Applied Physics

Year:

2009

Language:

english

File:

PDF, 309 KB

english, 2009

32

Electrical characteristics and short-channel effect of c -axis aligned crystal indium gallium zinc oxide transistor with short channel length

Kobayashi, Yoshiyuki, Matsuda, Shinpei, Matsubayashi, Daisuke, Suzawa, Hideomi, Sakakura, Masayuki, Hanaoka, Kazuya, Okazaki, Yutaka, Yamamoto, Tsutomu, Hondo, Suguru, Hamada, Takashi, Sasagawa, Shiny

Journal:

Japanese Journal of Applied Physics

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

33

Selective delivery of 5-fluorouracil (5-FU) to i.p. tissues using 5-FU microspheres in rats

Hagiwara, Akeo, Sakakura, Chouhei, Tsujimoto, Hiroyuki, Imanishi, Tsutomu, Ohgaki, Masaharu, Yamasaki, Junya, Sawai, Kiyoshi, Takahashi, Toshio, Fujita, Takuya, Yamamoto, Akira, Muranishi, Shozo, Ikad

Journal:

Anti-Cancer Drugs

Year:

1997

File:

PDF, 395 KB

1997

34

Thrombomodulin accelerates activated protein C production and inhibits thrombin generation in the plasma of disseminated intravascular coagulation patients

Wada, Hideo, Sakakura, Miho, Kushiya, Fumihiko, Nisikawa, Masakatu, Onishi, Katsuya, Nakatani, Kaname, Shiku, Hiroshi, Nobori, Tsutomu

Journal:

Blood Coagulation & Fibrinolysis

Year:

2005

Language:

english

File:

PDF, 131 KB

english, 2005

35

Hematologic Findings Associated With Thrombocytopenia During the Acute Phase of Exanthem Subitum Confirmed by Primary Human Herpesvirus-6 Infection

Hashimoto, Hiroyuki, Maruyama, Hiroaki, Fujimoto, Kayoko, Sakakura, Tsutomu, Seishu, Sotoyuki, Okuda, Norihiko

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2002

Language:

english

File:

PDF, 294 KB

english, 2002

36

Inhibition of colon cancer cell proliferation by antisense oligonucleotides targeting the messenger RNA of the Ki-ras gene

Sakakura, Chouhei, Haglwara, Akeo, Tsujimoto, Hiroyuki, Ozaki, Kimihiko, Sakakibara, Tuguo, Oyama, Takayuki, Ogaki, Masaharu, Imanishi, Tsutomu, Yamazaki, Junya, Takahashi, Toshio

Journal:

Anti-Cancer Drugs

Year:

1995

File:

PDF, 597 KB

1995

37

SPIE Proceedings [SPIE SPIE LASE - San Francisco, California, USA (Saturday 22 January 2011)] Laser Applications in Microelectronic and Optoelectronic Manufacturing (LAMOM) XVI - Three-dimensional structuring inside transparent materials by a phase modulated fs laser beam with a LCOS-SLM

Sakakura, Masaaki, Gu, Bo, Hennig, Guido, Miura, Kiyotaka, Sawano, Tsutomu, Xu, Xianfan, Niino, Hiroyuki, Shimotsuma, Yasuhiko, Hirao, Kazuyuki

Year:

2011

Language:

english

File:

PDF, 1.65 MB

english, 2011

38

Selective drug delivery to peri-tumoral region and regional lymphatics by local injection of aclarubicin adsorbed on activated carbon particles in patients with breast cancer???a pilot study

Hagiwara, Akeo, Takahashi, Toshio, Sawai, Kiyoshi, Sakakura, Chouhei, Shirasu, Morio, Ohgaki, Masaharu, Imanishi, Tsutomu, Yamasaki, Junya, Takemoto, Youichi, Kageyama, Norio

Journal:

Anti-Cancer Drugs

Year:

1997

File:

PDF, 360 KB

1997

39

New formulation of 5-fluorouracil in microspheres reduces toxicity in mice

Hagiwara, Akeo, Sakakura, Chouhei, Tsujimoto, Hiroyuki, Ohgaki, Masaharu, Imanishi, Tsutomu, Yamazaki, Junya, Sawai, Kiyoshi, Takahashi, Toshio, Yamamoto, Akira, Muranishi, Shozo, Tabata, Yasuhiko, Ik

Journal:

Anti-Cancer Drugs

Year:

1996

File:

PDF, 305 KB

1996

40

Prevention of peritoneal metastasis of cancer with dextran sulfate???an experimental study in mice

Hagiwara, Akeo, Sawai, Kiyoshi, Sakakura, Chouhei, Shirasu, Morio, Ohgaki, Masaharu, Imanishi, Tsutomu, Yamasaki, Junya, Togawa, Tsuyoshi, Takahashi, Toshio

Journal:

Anti-Cancer Drugs

Year:

1997

File:

PDF, 245 KB

1997

41

Cisplatin microcrystals suspended in oil

Tsujimoto, Hiroyuki, Sasaki, Sadayuki, Osaki, Kimihiko, Ohyama, Takayuki, Ohgaki, Masaharu, Imanishi, Tsutomu, Yamazaki, Junya, Sakakura, Chouhei, Hagiwara, Akeo, Takahashi, Toshio

Journal:

Anti-Cancer Drugs

Year:

1996

File:

PDF, 682 KB

1996

42

Stress-Induced Activation of Phosphorylase in the Rat Adenohypophysis

HIROSHIGE, TSUTOMU, SAKAKURA, MUNEKI

Journal:

Endocrinologia Japonica

Year:

1969

Language:

english

File:

PDF, 358 KB

english, 1969

43

Diurnal Variation of Corticotropin-Releasing Activity in the Rat Hypothalamus

HIROSHIGE, TSUTOMU, SAKAKURA, MUNEKI, ITOH, SHINJI

Journal:

Endocrinologia Japonica

Year:

1969

Language:

english

File:

PDF, 378 KB

english, 1969

44

Horizontal Variant of Benign Paroxysmal Positional Vertigo.

TAKEUCHI, Kazuhiko, NONOYAMA, Tsutomu, IMANISHI, Yoshinori, SAKAKURA, Yasuo

Journal:

Practica Oto-Rhino-Laryngologica

Year:

1998

File:

PDF, 629 KB

1998

45

Management of chronic sinusitis in children.

NONOYAMA, TSUTOMU, MAJIMA, YUICHI, NISHII, SATSUKI, OKADA, EISAKU, TAKAHASHI, YUKIMITSU, YUTA, ATSUSHI, SAKAKURA, YASUO

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1990

File:

PDF, 483 KB

1990

46

EFFECTS OF FREQUENT ANTRAL LAVAGE ON CHRONIC SINUSITIS IN CHILDREN

NISHI, SATSUKI, MAJIMA, YUICHI, NONOYAMA, TSUTOMU, OKADA, EISAKU, TAKAHASHI, YUKIMITSU, YUTA, ATSUSHI, SAKAKURA, YASUO

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1991

File:

PDF, 2.22 MB

1991

47

Surgical Management of Pediatric Sinusitis.

NONOYAMA, Tsutomu, MAJIMA, Yuichi, KAWAGUCHI, Shinya, SHINOGI, Jun, FUJITA, Tomohiko, SAKAKURA, Yasuo

Journal:

Practica Oto-Rhino-Laryngologica

Year:

1996

Language:

english

File:

PDF, 699 KB

english, 1996

48

Canalith Repositioning Procedure in Benign Paroxysmal Positional Vertigo.

TAKEUCHI, Kazuhiko, NONOYAMA, Tsutomu, OKADA, Eisaku, MASUDA, Sawako, SAKAKURA, Yasuo

Journal:

Practica Oto-Rhino-Laryngologica

Year:

1996

File:

PDF, 544 KB

1996

49

Usher Syndrome Associated with Nasal Bleeding and Psychosis; A Case Report.

HARADA, Teruhiko, SHINOGI, Jun, NONOYAMA, Tsutomu, OHLAWA, Chikahisa, SAKAKURA, Yasuo

Journal:

Practica Oto-Rhino-Laryngologica

Year:

1998

File:

PDF, 3.32 MB

1998

50

Study on Endoscopic Sinus Surgery Management of Chronic Sinusitis with Nasal Polyps.

Nonoyama, Tsutomu, Majima, Yuichi, Arima, Shinobu, Takeuchi, Kazuhiko, Sakakura, Yasuo

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

2000

File:

PDF, 647 KB

2000

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